77 cases in France .. Symptoms .. Are they dangerous?

77 cases in France .. Symptoms .. Are they dangerous?

Derived from Delta and Omicron (formerly “Deltacron”), the XD variant is a recombinant of the Covid virus. It is said to have infected 77 people in France but is no more severe than the Omicron BA.2 variant. What are the symptoms of variable XD? Is it (more) dangerous? I know everything.

one can They have two different types of covid same time. The XD variable is a file recombinant From Delta and Omicron (formerly “Deltacrone”). Recombinant XD is always detected at low levels (0.2% During the Flash Week 16 survey (April 18-24) and Not detected at week 17 (April 25 – May 1, 2022)” pointed Public health in France in the epidemiological update on May 12. 77 variable injuries XD The investigation was carried out by the regional units of public health in France according to a risk analysis on April 20. Eight hospital admission Reported but There are no critical care cases or deaths with variable XD. “This recombinant was detected at very low levels in France, which is favored by There is no competitive advantage for this variant compared to Omicron BA.2. The other alleles are Delta/Omicron, named XF and XSFeatured in other countries under similar conditions“The WHO defines. How many cases specifically in France? What formations? Instead of young people or old people? How do you know if you have a variant XD ? what is it symptoms Normal? more dangerous >> adjective What omicron? Latest information.

Definition: What is an XD variant?

“When two variables are traded at the same time, some people can Affected by two variants simultaneously. This common infection can lead to recombination phenomenaby saying that The exchange of genetic material between the two variantsRemember Public Health France. Therefore the recombinant has a genome that is partly identical to that first variant and partly to the second variant. The The XD variant was first discovered in early January 2022And It really is a combination because he has Genetic properties of two VOCs (variants) delta and omicron (BA.1).” Public Health France reported in its risk analysis on March 25.The XD Pangolin Dynasty This combination is assigned And It is now the official name for this recombinant (formerly Deltacrone). This variable has been classified as a VUM (Variable Under Control) i.e. “Variable under evaluation”. Recombination phenomenon is frequent for SARS-CoV-2 and Its importance in public health depends on the similarity of characteristics (transmissibility, pathogenicity, immune escape) between the two parental variants:

► If they have different characteristics, such as Delta and Omicron, Enhanced monitoring is essential To characterize the recombinant (transmissibility, pathogenicity, immune escape) likely to modify the dynamics of the COVID-19 epidemic.
► The more similar the parental variables are, the lower the probability that the recombinant material will have different properties.

None of the cases of the XD variant affected people over 70 years of age.

How many cases of XD variant are there in France?

In France, between December 2021 and January 2022, the Delta/Omicron joint trading was linked to the emergence of the XD recombinant. As of April 15, 77 cases of XD variant infection (54 confirmed and 23 suspected cases not sequenced but linked to a confirmed case) investigated by the regional public health units in France. These sequences correspond to cases from several regions. Thus the XD variant represents less than 0.1% of the interpretable sequences. “The average age of the cases was 37 yearsThe youngest case is 4 years old and the oldest is 86 years old. He was middle aged Similar to cases of omicron infectionIt was investigated between November 2021 and January 2022.” Six cases of the XD variant reported a previous infection by SARS-CoV-2 (8.1%), a lower proportion of omicron infections (14%).

What are the symptoms of variable XD?

According to the French public health, the The most common symptoms observed in people with the XD variant are: Asthenia/tired (58%)And headache (56%), fever (46%), Cough (42%) and sore throat (38%). The main difference with the previously investigated cases of omicron infection is the higher rate the age [perte du goût] and loss of smell [perte d’odorat].

Symptomatic 77 XD variant cases compared to previously investigated omicron cases. 04/20/2022 © Public Health France

These recombinants are difficult to detect because it is not known at first glance whether we are dealing with a co-infection or a hybrid. This is a high-flying work in genomics.And“Professor Bruno Lina, virologist, reports to France Inter on Tuesday 1 March 2022. It was in the framework of the sequencing conducted during the Flash surveys where the first cases of co-infection and recombination appeared.in France, Enhanced delta/omicron cross-infection monitoring has been developed in order to detect potential recombinants as soon as possible.Public Health France. Before remembering the context:Since the end of 2021, the Omicron wave has overlapped with the Delta wave in several regions of the world. This co-circulation of two variants broadly increases the likelihood of co-infection and thus the likelihood of recombinant infection. Several suspected delta/omicron . recombinants have been recently reported In the United Kingdom, the United States and AustraliaOthers are under investigation“.

Is the XD variant more dangerous than the Omicron?

The XD variant is not associated with a higher risk than the Omicron variant or the Delta variant, according to health authorities’ notes. Eight hospital admission The investigated cases of infection with the XD variant were reported, four of whom were part of the hospitalization cohort and were hospitalized for a reason other than COVID-19. “No admissions for critical care, no deathsThis has been reported, but longitudinal follow-up will be needed to confirm this“Saint-Public France reports on April 20”.This recombinant was detected at very low levels in France, which is favored by No competitive advantage for this variant compared to Omicron BA.2The WHO adds.

sources:

– Risk analysis related to emerging variants of Sars-Covid-2, 20 April 2022, Santé Publique France.

Coronavirus: Circulation of SARS-CoV-2 variants, updated March 23, 2022, Public Health France.

– Quick Surveys: Evaluation of the circulation of SARS-CoV-2 variants in France, updated February 28, 2022, Public Health France.

2022-05-14 16:31:42

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