Time-restricted eating may reduce cardiovascular disease risk in older breast cancer survivors

Older breast cancer survivors with cardiac metabolic risk factors who restricted eating to eight hours on weekdays, followed by 16 hours of fasting, reduced their risk of cardiovascular disease (CVD) after a few weeks, according to a new research letter. Posted today in JACC: Cardiology. The study is part of an upcoming mini-focus issue, “Physical Activity and Lifestyle Interventions in Cancer.”

The authors studied 22 individuals with a BMI who were classified as overweight or obese (>25 kg/m).2), had completed cardiotoxic therapy (anthracyclines, a drug commonly used in chemotherapy) within the past one to six years, and the median age was 66 years. For eight weeks, participants were allowed to eat freely between 12 and 8 p.m. on weekdays and at any time on weekends. Outside of those hours, participants were asked to drink only water, black coffee, or black tea. Using the Canadian Cardiovascular Society scoring system to calculate the 10-year Framingham risk score, the authors found that CVD risk decreased from 10.9% to 8.6% at the end of the trial period.

Bonnie Kee, MD, MSCE, editor-in-chief of JACC: Cardiology. “For example, what is the basis for interindividual variability in response to time-restricted eating in the Framingham risk score, and will this help determine which patients are most likely to benefit from this strategy? How does diet quality affect these outcomes? We look forward to seeing research that It uses practical lifestyle interventions that continue to evolve and advance to improve the lives of our patients and survivors.”

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2022-05-17 19:47:51

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